Col11a1 Regulates Bone Microarchitecture during Embryonic Development

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Col11a1 Regulates Bone Microarchitecture during Embryonic Development

Collagen XI alpha 1 (Col11a1) is an extracellular matrix molecule required for embryonic development with a role in both nucleating the formation of fibrils and regulating the diameter of heterotypic fibrils during collagen fibrillar assembly. Although found in many different tissues throughout the vertebrate body, Col11a1 plays an essential role in endochondral ossification. To further underst...

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ژورنال

عنوان ژورنال: Journal of Developmental Biology

سال: 2015

ISSN: 2221-3759

DOI: 10.3390/jdb3040158